Gene ID |
N/A |
Accession |
NM_003688 |
Alternative Name |
CAGH39; CAMGUK; CMG; FGS4; LIN2; MICPCH; TNRC8 |
Species |
Human |
Source |
Insect cells |
Description |
CASK is a calcium/calmodulin-dependent serine protein kinase which is a MAGUK (membrane-associated guanylate kinase) protein family member . CASK is a scaffold protein and the encoded protein is located at synapses in the brain. CASK associates with FG syndrome 4, mental retardation, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. CASK functions as a cytoskeletal membrane scaffold that coordinates signal transduction pathways within the cortical cytoskeleton . |
Accession |
NM_003688 |
Functions |
The specific activity of CASK was determined to be 3 nmol /min/mg as per activity assay protocol. |
Formulation |
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Solubility |
N/A |
Appearance |
Liquid |
Molecular Weight |
95 |
Purity |
70% – 90% |
Shipping Condition |
Dry Ice |
Storage Condition |
Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |