Gene ID |
N/A |
Accession |
NM_005975 |
Alternative Name |
PTK6; FLJ42088 |
Species |
Human |
Source |
Insect cells |
Description |
?BRK is a member of the non-receptor tyrosine kinases (PTKs) that contains an amino terminal SH3 and SH2 domain as well as the catalytic domain . BRK expression is low or undetectable in normal mammary tissue and benign lesions. However, approximately two-thirds of breast tumors express appreciable levels, and 27% of tumors over express BRK by fivefold or more .? |
Accession |
NM_005975 |
Functions |
The specific activity of BRK was determined to be 133 nmol /min/mg as per activity assay protocol. |
Formulation |
50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Solubility |
N/A |
Appearance |
Liquid |
Molecular Weight |
80 |
Purity |
70% – 90% |
Shipping Condition |
Dry Ice |
Storage Condition |
Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |