Gene ID |
N/A |
Accession |
BC007371 |
Alternative Name |
MGC10442 |
Species |
Human |
Source |
Insect cells |
Description |
BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain consensus sequences of the src protein tyrosine kinase family. BLK is expressed specifically in the B cell lineage and plays a role in signal transduction pathway that is restricted to B lymphoid cells . Stimulation of resting B-lymphocytes with antibodies to surface immunoglobulin (sIgD or sIgM) induces activation of BLK .? |
Accession |
BC007371 |
Functions |
The specific activity of BLK was determined to be 112 nmol /min/mg as per activity assay protocol. |
Formulation |
50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Solubility |
N/A |
Appearance |
Liquid |
Molecular Weight |
84 |
Purity |
70% – 90% |
Shipping Condition |
Dry Ice |
Storage Condition |
Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |