Recombinant Human AMPK (A2/B1/G2) (N-GST/C-His tag)

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Recombinant Human AMPK (A2/B1/G2) (N-GST/C-His tag)

Quantity: 10 μg
Gene Symbol: AMPK (A2/B1/G2)
Product Details
Gene ID N/A
Accession NM_006252, NM_006253, NM_001040633
Alternative Name Subunit A2: PRKAA2, AMPK, AMPK2, PRKAA Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G2: PRKAG2, AAKG, CMH6, WPWS, AAKG2, H91620p
Species Human
Source Insect cells
Description AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis . AMPK exists as a heterotrimeric complex composed of a catalytic a subunit and regulatory beta and gamma subunits. Binding of AMP to the gamma subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKKbeta.
Accession NM_006252, NM_006253, NM_001040633
Functions The specific activity of AMPK was determined to be 350 nmol /min/mg as per activity assay protocol.
Formulation 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight 92
Purity 70% – 90%
Shipping Condition Dry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

 

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