Recombinant Human AMPK (A2/B1/G1) (C-His tag)

Recombinant Human AMPK (A2/B1/G1) (C-His tag)

Quantity: 10 μg
Gene Symbol: AMPK (A2/B1/G1)
Product Details
Gene ID N/A
Accession NM_006252, NM_006253, NM_002733
Alternative Name Subunits A2: PRKAA2, AMPK, AMPK2, PRKAA Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G1: PRKAG1, AMPKG, MGC8666
Species Human
Source Insect cells
Description AMPK (A2/B1/G1) plays a key role in insulin signaling pathway and is a major therapeutic target for the treatment of diabetes . AMPK is viewed as a fuel sensor for glucose and lipid metabolism by modulating the activity of the autonomous nervous system in vivo. Short-term overexpression of a constitutively active form of AMPK in the liver leads to mild hypoglycemia and fatty liver due to increased fatty acid utilization .
Accession NM_006252, NM_006253, NM_002733
Functions The specific activity of AMPK was determined to be 310 nmol /min/mg as per activity assay protocol.
Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight 69
Purity 70% – 90%
Shipping Condition Dry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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