Recombinant Human AMPK (A1/B2/G1) (C-His tag)

Recombinant Human AMPK (A1/B2/G1) (C-His tag)

Quantity: 10 μg
Gene Symbol: AMPK (A1/B2/G1)
Product Details
Gene ID N/A
Accession NM_006251, NM_005399, NM_002733
Alternative Name Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B2: PRKAB2, MGC61468 Subunit G1: PRKAG1, AMPKG, MGC8666
Species Human
Source Insect cells
Description AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress . AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The ? subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle .
Accession NM_006251, NM_005399, NM_002733
Functions The specific activity of AMPK was determined to be 349 nmol /min/mg as per activity assay protocol
Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight 68
Purity 70% – 90%
Shipping Condition Dry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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