Gene ID |
N/A |
Accession |
NM_006251, NM_005399, NM_002733 |
Alternative Name |
Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B2: PRKAB2, MGC61468 Subunit G1: PRKAG1, AMPKG, MGC8666 |
Species |
Human |
Source |
Insect cells |
Description |
AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress . AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The ? subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle . |
Accession |
NM_006251, NM_005399, NM_002733 |
Functions |
The specific activity of AMPK was determined to be 349 nmol /min/mg as per activity assay protocol |
Formulation |
50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. |
Solubility |
N/A |
Appearance |
Liquid |
Molecular Weight |
68 |
Purity |
70% – 90% |
Shipping Condition |
Dry Ice |
Storage Condition |
Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |