Aldehyde Oxidase (AOX1) (NM_001159) Human Recombinant Protein

Quantity: 20 µg
Gene Symbol: AOX1
Catalogue Number: 2670002
Product Overview

Human Aldehyde Oxidase 1 (AOX1) recombinant protein, expressed in HEK293 cells and carrying a C-Myc/DDK tag. The product is supplied at 20 µg with a predicted molecular weight of 147.7 kDa and purity greater than 80%, as determined by SDS-PAGE and Coomassie blue staining.

Biological Summary

Aldehyde oxidase generates hydrogen peroxide and, under certain conditions, may also catalyze the formation of superoxide. It is considered a candidate gene associated with amyotrophic lateral sclerosis.

Purification and Handling

Recombinant protein was captured through an anti-DDK affinity column followed by conventional chromatography steps. For testing in cell culture applications, filter before use; some protein loss may occur during filtration.

Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol.

Storage: Store at -80°C. Stable for 12 months from the date of receipt under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Expression cDNA Clone / Amino Acid Sequence

Clone: RC219221 representing NM_001159. The following sequence is reproduced from the supplied datasheet (the original PDF identifies cloning-site and tag residues by color).

Refer Datasheet

For research use only, not for clinical diagnosis.

Product Details
Catalogue Number 2670002
Product Type Recombinant Proteins
Gene Symbol AOX1
Gene ID (Locus ID) 316
Accession NM_001159
Alternative Name AO; AOH1
Species Human
Source / Expression Host HEK293
Description Recombinant protein of human aldehyde oxidase 1 (AOX1), 20 µg
Functions Aldehyde oxidase generates hydrogen peroxide and, under certain conditions, may also catalyze the formation of superoxide. It is considered a candidate gene associated with amyotrophic lateral sclerosis.
Formulation / Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Solubility Not specified in datasheet
Appearance Not specified in datasheet
Molecular Weight 147.7 kDa (predicted)
Purity >80% as determined by SDS-PAGE and Coomassie blue staining
Shipping Condition Not specified in datasheet
Storage Condition Store at -80°C. Avoid repeated freeze-thaw cycles.
Quantity 20 µg
Tag C-Myc/DDK
Concentration >0.05 µg/µL as determined by microplate BCA method
Expression cDNA Clone RC219221 representing NM_001159
Preparation Recombinant protein was captured through an anti-DDK affinity column followed by conventional chromatography steps. For testing in cell culture applications, filter before use; some protein loss may occur during filtration.
Stability Stable for 12 months from the date of receipt under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
RefSeq NP_001150
UniProt ID Q06278
RefSeq Size 4949
RefSeq ORF 4014
Cytogenetics 2q33.1
Protein Families Druggable Genome
Protein Pathways Drug metabolism – cytochrome P450; Metabolic pathways; Nicotinate and nicotinamide metabolism; Tryptophan metabolism; Tyrosine metabolism; Valine, leucine and isoleucine degradation; Vitamin B6 metabolism.
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