Showing 1–9 of 69 results
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Pname
Product Details
Gene ID gene_id Accession accession Alternative Name alternative_name Species species Source source Description description Accession accession Functions functions Formulation formulation Solubility solubility Appearance appearance Molecular Weight molecular_weight Purity purity Concentration concentration Shipping Condition shipping_condition Storage Condition storage_condition $0.00(No) -
Recombinant Human 4-1BB Receptor (TNFRSF9)
Product Details
Gene ID 3604 Accession Q07011 Alternative Name Tumor necrosis factor receptor superfamily member 9, 41BB, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137<br/>Recombinant Human 4-1BB (TNFRSF9) Species Human Source E. coli Description 4-1BB Receptor (CD137) is a member of the TNF receptor superfamily expressed on activated CD4 and CD8 T cells as well as on activated natural killer cells. The binding of 4-1BB Receptor to its TNF family ligand, 4-1BB ligand (4-1BBL) delivers a co-stimulatory signal to resting T cells leading to high level IL2 production independently of CD28 signaling. Recombinant Human 4-1BB Receptor represents the soluble, cysteine-rich TNFR-like extracellular domain of 4-1BB Receptor. Accession Q07011 Functions The ED50 as determined by dose dependent proliferation of human megakaryocytic leukemia cell line is <0.5ng/ml. Formulation Lyophilized from 0.2 ?m filtered solution in PBS (pH 7.5) Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 18 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method Shipping Condition Ambient Temperature Storage Condition Recombinant 4-1BB Receptor can be stored in working aliquots at 2? – 8?C for one month, or at -20?C to -70?C for twelve months. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human 4-1BB Receptor (TNFRSF9)
Product Details
Gene ID 3604 Accession Q07011 Alternative Name Tumor necrosis factor receptor superfamily member 9, 41BB, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137<br/>Recombinant Human 4-1BB (TNFRSF9) Species Human Source E. coli Description 4-1BB Receptor (CD137) is a member of the TNF receptor superfamily expressed on activated CD4 and CD8 T cells as well as on activated natural killer cells. The binding of 4-1BB Receptor to its TNF family ligand, 4-1BB ligand (4-1BBL) delivers a co-stimulatory signal to resting T cells leading to high level IL2 production independently of CD28 signaling. Recombinant Human 4-1BB Receptor represents the soluble, cysteine-rich TNFR-like extracellular domain of 4-1BB Receptor. Accession Q07011 Functions The ED50 as determined by dose dependent proliferation of human megakaryocytic leukemia cell line is <0.5ng/ml. Formulation Lyophilized from 0.2 ?m filtered solution in PBS (pH 7.5) Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 18 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human 4-1BB Receptor (TNFRSF9)
Product Details
Gene ID 3604 Accession Q07011 Alternative Name Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD_antigen=CD137, CD137, ILA<br/>Recombinant Human 4-1BB (TNFRSF9) Species Human Source CHO cells Description 4-1BB Receptor (CD137) is a member of the TNF receptor superfamily expressed on activated CD4 and CD8 T cells as well as on activated natural killer cells. The binding of 4-1BB to its TNF family ligand, 4-1BB ligand (4-1BBL) delivers a costimulatory signal to resting T cells leading to high level IL-2 production independently of CD28 signaling. Accession Q07011 Functions The activity was tested by the ability of immobilized recombinant mouse 4-1BBL to bind human 4-1BB with a linear range of 10-500 ng/mL. Formulation Recombinant Human CD137 is lyophilized from 0.2 ?m filtered PBS solution, pH7.2. Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 65 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition Recombinant Human CD137 can be stored in working aliquots at 2? – 8?C for one month, or at -20?C to -70?C for twelve months. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human 4-1BB Receptor (TNFRSF9)
Product Details
Gene ID 3604 Accession Q07011 Alternative Name Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD_antigen=CD137, CD137, ILA<br/>Recombinant Human 4-1BB (TNFRSF9) Species Human Source CHO cells Description 4-1BB Receptor (CD137) is a member of the TNF receptor superfamily expressed on activated CD4 and CD8 T cells as well as on activated natural killer cells. The binding of 4-1BB to its TNF family ligand, 4-1BB ligand (4-1BBL) delivers a costimulatory signal to resting T cells leading to high level IL-2 production independently of CD28 signaling. Accession Q07011 Functions The activity was tested by the ability of immobilized recombinant mouse 4-1BBL to bind human 4-1BB with a linear range of 10-500 ng/mL. Formulation Recombinant Human CD137 is lyophilized from 0.2 ?m filtered PBS solution, pH7.2. Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 65 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition Recombinant Human CD137 can be stored in working aliquots at 2? – 8?C for one month, or at -20?C to -70?C for twelve months. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human 4-BBL (TNFSF9)
Product Details
Gene ID 8744 Accession P41273 Alternative Name TNFSF9, CD137L, 4BBL Species Human Source E. coli Description Human 4-BBL or TNFSF9 is a member of the TNF superfamily. It is a type 2 transmembrane protein expressed on activated T-cells. It is a bidirectional signal transducer which acts as a costimulatory receptor molecule on T lymphocytes. Its functions primarily stimulate the immune response by promoting the release of cytokines such as IL-2 and IFN-gamma. TNFSF9 works with TNFRSF9 for the generation of cytotoxic T cells, proliferation of T-cells as well as antigen presentation. It also reactivates T lymphocytes which have become anergic. It is also expressed on activated NK cells, B-cells, macrophages, dendritic cells and some brain cells. Recombinant Human 4-BBL is a 19.6 kDa protein. Accession P41273 Functions coming soon Formulation coming soon Solubility N/A Appearance Lyophilized Powder Molecular Weight 19.6 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human 4-BBL (TNFSF9)
Product Details
Gene ID 8744 Accession P41273 Alternative Name TNFSF9, CD137L, 4BBL Species Human Source E. coli Description Human 4-BBL or TNFSF9 is a member of the TNF superfamily. It is a type 2 transmembrane protein expressed on activated T-cells. It is a bidirectional signal transducer which acts as a costimulatory receptor molecule on T lymphocytes. Its functions primarily stimulate the immune response by promoting the release of cytokines such as IL-2 and IFN-gamma. TNFSF9 works with TNFRSF9 for the generation of cytotoxic T cells, proliferation of T-cells as well as antigen presentation. It also reactivates T lymphocytes which have become anergic. It is also expressed on activated NK cells, B-cells, macrophages, dendritic cells and some brain cells. Recombinant Human 4-BBL is a 19.6 kDa protein. Accession P41273 Functions coming soon Formulation coming soon Solubility N/A Appearance Lyophilized Powder Molecular Weight 19.6 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human ABL1 (N-His tag)
Product Details
Gene ID N/A Accession NM_005157 Alternative Name ABL; JTK7; p150; c-ABL; v-abl; bcr/abl Species Human Source Insect cells Description ?ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene . Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia . The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDK1-mediated phosphorylation, suggesting a cell cycle function for ABL1. Accession NM_005157 Functions The specific activity of ABL1 was determined tobe 871 nmol/min/mg as per activity assay protocol Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. Solubility N/A Appearance Liquid Molecular Weight 135 Purity 70% – 90% Shipping Condition Dry Ice Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles $0.00(No) -
Recombinant Human ABL2 (N-His tag)
Product Details
Gene ID N/A Accession NM_005158 Alternative Name ARG; ABLL Species Human Source Insect cells Description ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is involved in translocation with the ETV6 gene in human leukemia and has an altered expression in several human carcinomas . Two isoforms of ABL2 with different N-termini (1A and 1B) have been identified. The C-terminal domain of ABL2 contains two F-actin-binding sequences that perform a number of actions related to cell morphology and motility by interacting with actin filaments .? Accession NM_005158 Functions The specific activity of ABL2 was determined tobe 1218 nmol/min/mg as per activity assay protocol Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. Solubility N/A Appearance Liquid Molecular Weight 132 Purity 70% – 90% Shipping Condition Dry Ice Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. $0.00(No)