Gene ID |
N/A |
Accession |
NM_172226 |
Alternative Name |
CAMKK; CAMKKB; KIAA0787; MGC15254 |
Species |
Human |
Source |
Insect cells |
Description |
CAMKK2 (CAMKK?) is a member of the CAMKK family. It is broadly distributed in tissues with highest levels in brain, thymus, spleen, and testis . CaMKK2 undergoes intramolecular autophosphorylation, is regulated by Ca2+/calmodulin and phosphorylates CaMKI and CaMKIV on Thr177 and Thr200, respectively. CaMKK2 activates both CaMKI and CaMKIV when coexpressed in Jurkat T cells. CaMKK2 also phosphorylates and regulates the activity of AMPK, which is an important regulator of cellular metabolism in response to metabolic stress . |
Accession |
NM_172226 |
Functions |
The specific activity of CAMKK2 was determined to be 11 nmol /min/mgas per activity assay protocol. |
Formulation |
50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Solubility |
N/A |
Appearance |
Liquid |
Molecular Weight |
88 |
Purity |
70% – 90% |
Shipping Condition |
Dry Ice |
Storage Condition |
Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |