Recombinant Human CAMKK2 (N-GST tag)
Product Details
| Gene ID | N/A |
| Accession | NM_172226 |
| Alternative Name | CAMKK; CAMKKB; KIAA0787; MGC15254 |
| Species | Human |
| Source | Insect cells |
| Description | CAMKK2 (CAMKK?) is a member of the CAMKK family. It is broadly distributed in tissues with highest levels in brain, thymus, spleen, and testis . CaMKK2 undergoes intramolecular autophosphorylation, is regulated by Ca2+/calmodulin and phosphorylates CaMKI and CaMKIV on Thr177 and Thr200, respectively. CaMKK2 activates both CaMKI and CaMKIV when coexpressed in Jurkat T cells. CaMKK2 also phosphorylates and regulates the activity of AMPK, which is an important regulator of cellular metabolism in response to metabolic stress . |
| Accession | NM_172226 |
| Functions | The specific activity of CAMKK2 was determined to be 11 nmol /min/mgas per activity assay protocol. |
| Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
| Solubility | N/A |
| Appearance | Liquid |
| Molecular Weight | 88 |
| Purity | 70% – 90% |
| Shipping Condition | Dry Ice |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
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