Gene ID |
608 |
Accession |
Q02223 |
Alternative Name |
Tumor necrosis factor receptor superfamily member 17, TNFRSF17, B cell maturation antigen, BCM, BCMA, CD269 |
Species |
Human |
Source |
E. coli |
Description |
BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is preferentially expressed in mature B lymphocytes.The N-terminal part of both mouse and human proteins contains a conserved six-cysteine motif. BLyS binds to three receptors of the TNF receptor family (B cell maturation antigen BCMA, TACI, and BAFF-R), all of which are expressed by mature B cells. |
Accession |
Q02223 |
Functions |
The ED(50) was determined by the dose-dependent proliferation of KMS15 cells and was found to be <0.05ng/mL. |
Formulation |
Lyophilized from a 0.2 ?m filtered solution in PBS |
Solubility |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Appearance |
Lyophilized Powder |
Molecular Weight |
6 |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
<1.0 EU/μg of recombinant protein as determined by the LAL method |
Shipping Condition |
Ambient Temperature |
Storage Condition |
The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |