Recombinant Human AMPK (A2/B2/G1) (C-His tag)

Gene ID	N/A
Accession	NM_006252, NM_005399, NM_002733
Alternative Name	Subunit A2: PRKAA2, AMPK, AMPK2, PRKAA Subunit B2: PRKAB2, MGC61468 Subunit G1: PRKAG1, AMPKG, MGC8666
Species	Human
Source	Insect cells
Description	AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis . AMPK exists as a heterotrimeric complex composed of a catalytic a subunit and regulatory ? and ? subunits. Binding of AMP to the ? subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKK? .
Accession	NM_006252, NM_005399, NM_002733
Functions	The specific activity of AMPK was determined to be 280 nmol/min/mg as per activity assay protocol.
Formulation	50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Solubility	N/A
Appearance	Liquid
Molecular Weight	69
Purity	70% – 90%
Shipping Condition	Dry Ice
Storage Condition	Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.