| Gene ID |
N/A |
| Accession |
NM_006251, NM_006253, NM_017431 |
| Alternative Name |
Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G3: PRKAG3 |
| Species |
Human |
| Source |
Insect cells |
| Description |
AMPK (A1/B1/G3) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress . AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The ? subunit is dominantly expressed in skeletal muscle where it may play a key role in the regulation of energy metabolism . |
| Accession |
NM_006251, NM_006253, NM_017431 |
| Functions |
The specific activity of AMPK was determined to be 185 nmol /min/mg as per activity assay protocol |
| Formulation |
50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. |
| Solubility |
N/A |
| Appearance |
Liquid |
| Molecular Weight |
68 |
| Purity |
70% – 90% |
| Shipping Condition |
Dry Ice |
| Storage Condition |
Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
