Recombinant Human AMPK (A1/B1/G2) (C-His tag)

Recombinant Human AMPK (A1/B1/G2) (C-His tag)

Quantity: 10 μg
Gene Symbol: AMPK (A1/B1/G2)
Product Details
Gene ID N/A
Accession NM_006251, NM_006253, NM_001040633
Alternative Name Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G2: PRKAG2, AAKG, CMH6, WPWS, AAKG2, H91620p
Species Human
Source Insect cells
Description AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis . AMPK exists as a heterotrimeric complex composed of a catalytic a subunit and regulatory ? and ? subunits. Binding of AMP to the ? subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKK?.
Accession NM_006251, NM_006253, NM_001040633
Functions The specific activity of AMPK was determined to be 980 nmol /min/mg as per activity assay protoco
Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight 68
Purity 70% – 90%
Shipping Condition Dry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles
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