Recombinant Human AMPK (A1/B1/G1) (C-His tag)

Recombinant Human AMPK (A1/B1/G1) (C-His tag)

Quantity: 10 μg
Gene Symbol: AMPK (A1/B1/G1)
Product Details
Gene ID N/A
Accession NM_006251, NM_006253, NM_002733
Alternative Name Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G1: PRKAG1, AMPKG, MGC8666
Species Human
Source Insect cells
Description AMPK is a heterotrimer protein kinase consisting of an a catalytic subunit, and non-catalytic ? and ? subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status . In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol .
Accession NM_006251, NM_006253, NM_002733
Functions The specific activity of AMPK was determined to be 737 nmol /min/mg as per activity assay protocol.
Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight 68
Purity 70% – 90%
Shipping Condition Dry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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