Gene ID |
N/A |
Accession |
NM_006251, NM_006253, NM_002733 |
Alternative Name |
Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G1: PRKAG1, AMPKG, MGC8666 |
Species |
Human |
Source |
Insect cells |
Description |
AMPK is a heterotrimer protein kinase consisting of an a catalytic subunit, and non-catalytic ? and ? subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status . In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol . |
Accession |
NM_006251, NM_006253, NM_002733 |
Functions |
The specific activity of AMPK was determined to be 737 nmol /min/mg as per activity assay protocol. |
Formulation |
50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. |
Solubility |
N/A |
Appearance |
Liquid |
Molecular Weight |
68 |
Purity |
70% – 90% |
Shipping Condition |
Dry Ice |
Storage Condition |
Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |