Recombinant Human ALK3 (BMPR1A) (N-GST tag)

Recombinant Human ALK3 (BMPR1A) (N-GST tag)

Quantity: 10 μg
Gene Symbol: ALK3 (BMPR1A)
Product Details
Gene ID N/A
Accession NM_004329
Alternative Name ALK3; BMPR1A; 10q23del; ACVRLK3; CD292; SKR5
Species Human
Source Insect cells
Description ?BMPR1A (also known as bone morphogenetic protein receptor 1A) is a member of the transmembrane serine/threonine kinase family that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A act as a minor susceptibility gene for PTEN-mutation-negative Cowden syndrome. BMPR1A regulates the PTEN protein levels by decreasing PTEN’s association with the degradative pathway . BMPR1A trafficking plays a significant role in FOP pathogenesis and is also involved in human T-cell differentiation .
Accession NM_004329
Functions The specific activity of ALK3 (BMPR1A) was determined to be 1.2 nmol /min/mg as per activity assay protocol.
Formulation 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight 66
Purity 70% – 90%
Shipping Condition Dry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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