Showing 28–36 of 84 results
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Recombinant Bangladesh strain Nipah virus Glycoprotein (partial, biotinylated)
Product Overview Details Species Henipavirus nipahense Background This recombinant Bangladesh strain glycoprotein (G) of Henipavirus nipahense, expressed in E. coli, corresponds to the viral attachment glycoprotein encoded by the G gene. It mediates high-affinity binding to host ephrin-B2 and ephrin-B3 receptors, a critical step in viral tropism and entry. The glycoprotein functions in concert with the fusion (F) protein to facilitate membrane fusion and viral internalization and is a major determinant of virulence and host immune recognition. As a principal antigenic component, it elicits potent neutralizing antibody responses. This recombinant protein can be used for serological diagnostics, epitope mapping, monoclonal antibody development, vaccine and immunogenicity studies, receptor-binding assays, and structural and functional characterization of Nipah virus glycoproteins. UniProt ID H6V875 Purity >85% as determined by SDS-PAGE Target Sequence Refer datasheet Stability & Storage For long-term preservation, the product should be maintained in a lyophilized form at temperatures between −20 °C and −80 °C. To ensure optimal stability, the protein should be aliquoted prior to storage. Once reconstituted, the protein solution may be stored at 2–8 °C for up to 2–7 days. Repeated freeze–thaw cycles should be avoided. Reconstitution The protein may be reconstituted in sterile water to prepare a stock solution. Repeated freeze–thaw cycles should be avoided. Non-biotinylated form of this glycoprotein is also available
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Recombinant Bangladesh strain Nipah virus Glycoprotein (partial)
Product Overview Details Species Henipavirus nipahense Background This recombinant Bangladesh strain glycoprotein (G) of Henipavirus nipahense, expressed in E. coli, corresponds to the viral attachment glycoprotein encoded by the G gene. It mediates high-affinity binding to host ephrin-B2 and ephrin-B3 receptors, a critical step in viral tropism and entry. The glycoprotein functions in concert with the fusion (F) protein to facilitate membrane fusion and viral internalization and is a major determinant of virulence and host immune recognition. As a principal antigenic component, it elicits potent neutralizing antibody responses. This recombinant protein can be used for serological diagnostics, epitope mapping, monoclonal antibody development, vaccine and immunogenicity studies, receptor-binding assays, and structural and functional characterization of Nipah virus glycoproteins. UniProt ID H6V875 Purity >85% as determined by SDS-PAGE Target Sequence Refer datasheet Stability & Storage For long-term preservation, the product should be maintained in a lyophilized form at temperatures between −20 °C and −80 °C. To ensure optimal stability, the protein should be aliquoted prior to storage. Once reconstituted, the protein solution may be stored at 2–8 °C for up to 2–7 days. Repeated freeze–thaw cycles should be avoided. Reconstitution The protein may be reconstituted in sterile water to prepare a stock solution. Repeated freeze–thaw cycles should be avoided. (No) -
Recombinant Human Adiponectin (Acrp30)
Product Details
Gene ID 9370 Accession Q15848 Alternative Name 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein Species Human Source E. coli Description Adiponectin is an adipose-derived secreted protein that influences the body?s response to insulin. Adiponectin belongs to the soluble defence collagen super family and is involved with the promotion of adipocyte differentiation, fatty acid catabolism, and insulin resistance. Recombinant adiponectin is a multimeric glycoprotein that also has anti-inflammatory effects on the cell lining of blood vessel walls. High blood levels of adiponectin are associated with reduced risks of heart attacks while low levels are associated with obesity and an increased risk of heart attacks. Accession Q15848 Functions The ED50, as determined by a cytotoxic assay (using M1 cells) was found to be 3.0-6.0 μg/ml Formulation Lyophilized from a 0.2 ?m filtered solution in tris buffer with NaCl (pH 8) Solubility Reconstitute in sterile deionized water to 0.1 mg/ml Appearance Lyophilized Powder Molecular Weight 24.8 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human Adiponectin (Acrp30)
Product Details
Gene ID 9370 Accession Q15848 Alternative Name 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein Species Human Source E. coli Description Adiponectin is an adipose-derived secreted protein that influences the body?s response to insulin. Adiponectin belongs to the soluble defence collagen super family and is involved with the promotion of adipocyte differentiation, fatty acid catabolism, and insulin resistance. Recombinant adiponectin is a multimeric glycoprotein that also has anti-inflammatory effects on the cell lining of blood vessel walls. High blood levels of adiponectin are associated with reduced risks of heart attacks while low levels are associated with obesity and an increased risk of heart attacks. Accession Q15848 Functions The ED50 , as determined by a cytotoxic assay (using M1 cells) was found to be 3.0-6.0 μg/ml Formulation Lyophilized from a 0.2 ?m filtered solution in PBS Solubility Reconstitute in sterile deionized water to 0.1 mg/mL Appearance Lyophilized Powder Molecular Weight 24.8 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human AIMP1
Product Details
Gene ID 9255 Accession Q12904 Alternative Name EMAP II, EMAP-2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1, SCYE1<br/>Recombinant Human Endothelial Monocyte-Activating Polypeptide 2 (AIMP1) Species Human Source E. coli Description EMAP-II is activated during apoptosis by cleavage of pro-EMAP through caspase 8 and enhances the recruitment of inflammatory cells by its chemotactic properties. Besides its chemotactic effect on inflammatory cells, EMAP-II increases the adhesiveness of coronary artery smooth muscle cells (CASMC) for monocytes. EMAP-II also has anti-angiogenic properties, which are explained by its pro-apoptotic effect on endothelial cells. Accession Q12904 Functions The ED(50) was determined by apoptotic effect on MCF-7 cells using a concentration of 10-50 ng/mL. Formulation Recombinant EMAP-II was lyophilized from a 0.2 ?m filtered 20 mM PB,130 mM NaCl solution pH 7.5. Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 18 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human AIMP1
Product Details
Gene ID 9255 Accession Q12904 Alternative Name EMAP II, EMAP-2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1, SCYE1<br/>Recombinant Human Endothelial Monocyte-Activating Polypeptide 2 (AIMP1) Species Human Source E. coli Description EMAP-II is activated during apoptosis by cleavage of pro-EMAP through caspase 8 and enhances the recruitment of inflammatory cells by its chemotactic properties. Besides its chemotactic effect on inflammatory cells, EMAP-II increases the adhesiveness of coronary artery smooth muscle cells (CASMC) for monocytes. EMAP-II also has anti-angiogenic properties, which are explained by its pro-apoptotic effect on endothelial cells. Accession Q12904 Functions The ED(50) was determined by apoptotic effect on MCF-7 cells using a concentration of 10-50 ng/mL. Formulation Recombinant EMAP-II was lyophilized from a 0.2 ?m filtered 20 mM PB,130 mM NaCl solution pH 7.5. Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 18 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human AITRL (TNFSF18)
Product Details
Gene ID 8995 Accession Q9UNG2 Alternative Name Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18) Species Human Source E. coli Description TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4-CD8 double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18’s expression is transiently up-regulated by proinflammatory stimulation. Accession Q9UNG2 Functions N.A. Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. Solubility Reconstitute at 100 μg/mL in PBS containing at least 0.1% human or bovine serum albumin. Appearance Lyophilized Powder Molecular Weight 14.2 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° – 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human AITRL (TNFSF18)
Product Details
Gene ID 8995 Accession Q9UNG2 Alternative Name Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18) Species Human Source E. coli Description TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4-CD8 double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18’s expression is transiently up-regulated by proinflammatory stimulation. Accession Q9UNG2 Functions N.A. Formulation Lyophilized from a 0.2 micron filtered solution in Tris and salt Solubility Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin. Appearance Lyophilized Powder Molecular Weight 14.2 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No) -
Recombinant Human AITRL (TNFSF18)
Product Details
Gene ID 8995 Accession Q9UNG2 Alternative Name Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18) Species Human Source E. coli Description TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4-CD8 double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18’s expression is transiently up-regulated by proinflammatory stimulation. Accession Q9UNG2 Functions N.A. Formulation Lyophilized from a 0.2 micron filtered solution in Tris and salt Solubility Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin. Appearance Lyophilized Powder Molecular Weight 14.2 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. $0.00(No)