Showing 10–18 of 59 results
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Recombinant Human AIMP1
Product Details
Gene ID 9255 Accession Q12904 Alternative Name EMAP II, EMAP-2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1, SCYE1<br/>Recombinant Human Endothelial Monocyte-Activating Polypeptide 2 (AIMP1) Species Human Source E. coli Description EMAP-II is activated during apoptosis by cleavage of pro-EMAP through caspase 8 and enhances the recruitment of inflammatory cells by its chemotactic properties. Besides its chemotactic effect on inflammatory cells, EMAP-II increases the adhesiveness of coronary artery smooth muscle cells (CASMC) for monocytes. EMAP-II also has anti-angiogenic properties, which are explained by its pro-apoptotic effect on endothelial cells. Accession Q12904 Functions The ED(50) was determined by apoptotic effect on MCF-7 cells using a concentration of 10-50 ng/mL. Formulation Recombinant EMAP-II was lyophilized from a 0.2 ?m filtered 20 mM PB,130 mM NaCl solution pH 7.5. Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 18 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. ₹0.00(No) -
Recombinant Human AIMP1
Product Details
Gene ID 9255 Accession Q12904 Alternative Name EMAP II, EMAP-2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1, SCYE1<br/>Recombinant Human Endothelial Monocyte-Activating Polypeptide 2 (AIMP1) Species Human Source E. coli Description EMAP-II is activated during apoptosis by cleavage of pro-EMAP through caspase 8 and enhances the recruitment of inflammatory cells by its chemotactic properties. Besides its chemotactic effect on inflammatory cells, EMAP-II increases the adhesiveness of coronary artery smooth muscle cells (CASMC) for monocytes. EMAP-II also has anti-angiogenic properties, which are explained by its pro-apoptotic effect on endothelial cells. Accession Q12904 Functions The ED(50) was determined by apoptotic effect on MCF-7 cells using a concentration of 10-50 ng/mL. Formulation Recombinant EMAP-II was lyophilized from a 0.2 ?m filtered 20 mM PB,130 mM NaCl solution pH 7.5. Solubility A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Appearance Lyophilized Powder Molecular Weight 18 Purity >95% as determined by SDS-PAGE Concentration <1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. ₹0.00(No) -
Recombinant Human AITRL (TNFSF18)
Product Details
Gene ID 8995 Accession Q9UNG2 Alternative Name Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18) Species Human Source E. coli Description TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4-CD8 double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18’s expression is transiently up-regulated by proinflammatory stimulation. Accession Q9UNG2 Functions N.A. Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. Solubility Reconstitute at 100 μg/mL in PBS containing at least 0.1% human or bovine serum albumin. Appearance Lyophilized Powder Molecular Weight 14.2 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° – 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. ₹0.00(No) -
Recombinant Human AITRL (TNFSF18)
Product Details
Gene ID 8995 Accession Q9UNG2 Alternative Name Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18) Species Human Source E. coli Description TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4-CD8 double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18’s expression is transiently up-regulated by proinflammatory stimulation. Accession Q9UNG2 Functions N.A. Formulation Lyophilized from a 0.2 micron filtered solution in Tris and salt Solubility Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin. Appearance Lyophilized Powder Molecular Weight 14.2 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. ₹0.00(No) -
Recombinant Human AITRL (TNFSF18)
Product Details
Gene ID 8995 Accession Q9UNG2 Alternative Name Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6<br/>Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18) Species Human Source E. coli Description TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4-CD8 double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18’s expression is transiently up-regulated by proinflammatory stimulation. Accession Q9UNG2 Functions N.A. Formulation Lyophilized from a 0.2 micron filtered solution in Tris and salt Solubility Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin. Appearance Lyophilized Powder Molecular Weight 14.2 Purity >95% as determined by SDS-PAGE Concentration < 1.0 EU/μg of recombinant protein as determined by the LAL method. Shipping Condition Ambient Temperature Storage Condition The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? – 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. ₹0.00(No) -
Recombinant Human AKT1 (N-GST tag)
Product Details
Gene ID N/A Accession NM_005163 Alternative Name PKB; RAC; PRKBA; MGC99656; RAC-ALPHA Species Human Source Insect cells Description AKT1/PKBa is a serine/threonine kinase that belongs to the AKT family. AKT1 is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility . AKT1 is frequently overexpressed and active in many types of human cancers including cancers of colon, breast, brain, pancreas and prostate as well as lymphomas and leukemias .? Accession NM_005163 Functions The specific activity of AKT1 was determined to be 125 nmol /min/mg as per activity assay protocol. Formulation 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. Solubility N/A Appearance Liquid Molecular Weight 85 Purity 70% – 90% Shipping Condition Dry Ice Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. ₹0.00(No) -
Recombinant Human AKT2 (N-GST tag)
Product Details
Gene ID N/A Accession NM_001626 Alternative Name PRKBB; PKBBETA; RAC-BETA Species Human Source Insect cells Description AKT2 or Protein Kinase B ? (PKB?) is a serine/threonine kinase that is a member of the AKT family. AKT2 like the other AKT members is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility. The PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of AKT2 to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1). Accession NM_001626 Functions The specific activity of AKT2 was determined to be 43 nmol /min/mg as per activity assay protocol. Formulation 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. Solubility N/A Appearance Liquid Molecular Weight 85 Purity 70% – 90% Shipping Condition Dry Ice Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. . ₹0.00(No) -
Recombinant Human AKT2 (N-His tag)
Product Details
Gene ID N/A Accession NM_001626 Alternative Name PRKBB; PKBBETA; RAC-BETA Species Human Source Insect cells Description AKT2 or Protein Kinase B ? (PKB?) is a serine/threonine kinase that is a member of the AKT family. AKT2 like the other AKT members is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility. The PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of AKT2 to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1). Accession NM_001626 Functions The specific activity of AKT2 was determined to be 44 nmol /min/mg as per activity assay protocol. Formulation 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. Solubility N/A Appearance Liquid Molecular Weight 58 Purity 70% – 90% Shipping Condition Dry Ice Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. ₹0.00(No) -
Recombinant Human AKT3 (N-GST tag)
Product Details
Gene ID N/A Accession NM_005465 Alternative Name PKBG; PRKBG; STK-2; RAC-gamma; RAC-PK-gamma; DKFZP434N0250 Species Human Source Insect cells Description ?AKT 3 or Protein Kinase B ? (PKB?) is a serine/threonine kinase that is a member of the AKT family. AKT 3 is activated in cells exposed to diverse stimuli such as hormones, growth factors, and extracellular matrix components . AKT 3 phosphorylates and regulates the function of many cellular proteins involved in processes that include cellular metabolism, survival/apoptosis, and proliferation. Recent evidence indicates that AKT 3 is frequently overexpressed in many types of human cancers including breast and prostate .? Accession NM_005465 Functions The specific activity of AKT3 was determined to be 206 nmol /min/mg as per activity assay protocol. Formulation 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. Solubility N/A Appearance Liquid Molecular Weight 85 Purity 70% – 90% Shipping Condition Dry Ice Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. ₹0.00(No)